Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2393935

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human liver V1A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Vasopressin V1a receptor (CHEMBL1889)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Carbon-11 N-methyl alkylation of L-368,899 and in vivo PET imaging investigations for neural oxytocin receptors.
Smith AL, Freeman SM, Voll RJ, Young LJ, Goodman MM.
Bioorg Med Chem Lett (2013) 23 : 902 -906
PubMed 23270988 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 6.48 6.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1253853 1 6.75
CHEMBL2391300 1 6.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1253853 Ki = 180.0 nM 6.75
CHEMBL2391300 Ki = 620.0 nM 6.21