Assay Detail
Binding
CHEMBL2394495
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Inhibition of MAO-A (unknown origin) by luciferase reporter gene assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Recent development of potent analogues of oxazolidinone antibacterial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 5.43 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18116 | TOLOXATONE | 4.0 | 1 | 5.82 |
| CHEMBL2391306 | — | — | 1 | 5.40 |
| CHEMBL2391305 | — | — | 1 | 5.40 |
| CHEMBL126 | LINEZOLID | 4.0 | 1 | 5.10 |
| CHEMBL1257051 | TEDIZOLID | 3.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18116 | TOLOXATONE | Ki | = | 1500.0 | nM | 5.82 |
| CHEMBL2391306 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL2391305 | — | Ki | = | 4000.0 | nM | 5.40 |
| CHEMBL126 | LINEZOLID | Ki | = | 7900.0 | nM | 5.10 |
| CHEMBL1257051 | TEDIZOLID | Ki | < | 2000.0 | nM | - |