Assay Detail
Functional
CHEMBL2399045
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Human rhinovirus C15 assessed as inhibition of viral RNA replication by luciferase reporter replicon assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human rhinovirus sp. |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.94 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2397315 | — | — | 1 | 7.35 |
| CHEMBL2397316 | — | — | 1 | 7.14 |
| CHEMBL2397317 | — | — | 1 | 6.70 |
| CHEMBL2397314 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2397315 | — | EC50 | = | 45.0 | nM | 7.35 |
| CHEMBL2397316 | — | EC50 | = | 72.0 | nM | 7.14 |
| CHEMBL2397317 | — | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2397314 | — | EC50 | = | 260.0 | nM | 6.58 |