Assay Detail
Binding
CHEMBL2399308
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of farnesyltransferase (unknown origin) assessed as HRAS farnesylation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.89 | 8.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL351706 | BMS-214662 | 1.0 | 1 | 8.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL351706 | BMS-214662 | IC50 | = | 1.3 | nM | 8.89 |