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Assay Detail

CHEMBL2399335

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Tcf4 binding to beta-catenin (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Catenin beta-1 (CHEMBL5866)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Direct targeting of β-catenin: Inhibition of protein-protein interactions for the inactivation of Wnt signaling.
Hahne G, Grossmann TN.
Bioorg Med Chem (2013) 21 : 4020 -4026
PubMed 23566764 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.35 6.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL254381 1 6.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL254381 Kd = 450.0 nM 6.35