Assay Detail
Binding
CHEMBL2399353
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Escherichia coli K-12 FimH assessed as dissociation constant by SPR analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli K-12 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Type 1 fimbrin D-mannose specific adhesin (CHEMBL4837) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli K-12 |
Publication
Thiazolylaminomannosides as potent antiadhesives of type 1 piliated Escherichia coli isolated from Crohn's disease patients.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 8.30 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1170455 | — | — | 1 | 8.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1170455 | — | Kd | = | 5.0 | nM | 8.30 |