Assay Detail
Functional
CHEMBL2400541
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Cytotoxicity against human HeLa cells assessed as growth inhibition after 72 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anticancer effects of a novel class rosin-derivatives with different mechanisms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.21 | 5.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2398552 | — | — | 1 | 5.49 |
| CHEMBL2398551 | — | — | 1 | 5.43 |
| CHEMBL2398555 | — | — | 1 | 5.35 |
| CHEMBL2398553 | — | — | 1 | 5.29 |
| CHEMBL2398554 | — | — | 1 | 5.24 |
| CHEMBL70488 | — | — | 1 | 5.12 |
| CHEMBL12850 | DEHYDROABIETIC ACID | — | 1 | 4.55 |
| CHEMBL170 | QUININE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2398552 | — | IC50 | = | 3210.0 | nM | 5.49 |
| CHEMBL2398551 | — | IC50 | = | 3730.0 | nM | 5.43 |
| CHEMBL2398555 | — | IC50 | = | 4470.0 | nM | 5.35 |
| CHEMBL2398553 | — | IC50 | = | 5120.0 | nM | 5.29 |
| CHEMBL2398554 | — | IC50 | = | 5760.0 | nM | 5.24 |
| CHEMBL70488 | — | IC50 | = | 7680.0 | nM | 5.12 |
| CHEMBL12850 | DEHYDROABIETIC ACID | IC50 | = | 28430.0 | nM | 4.55 |
| CHEMBL170 | QUININE | IC50 | > | 50000.0 | nM | - |