Assay Detail
Binding
CHEMBL2404844
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant MAOB using benzylamine as substrate incubated for 15 mins prior to substrate addition measured after 20 mins by fluorescence plate reader analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and evaluation of multitarget-directed resveratrol derivatives for the treatment of Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.73 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2402067 | — | — | 1 | 4.92 |
| CHEMBL2402160 | — | — | 1 | 4.85 |
| CHEMBL255231 | LADOSTIGIL | 2.0 | 1 | 4.43 |
| CHEMBL8706 | CLORGILINE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2402067 | — | IC50 | = | 12160.0 | nM | 4.92 |
| CHEMBL2402160 | — | IC50 | = | 14090.0 | nM | 4.85 |
| CHEMBL255231 | LADOSTIGIL | IC50 | = | 37100.0 | nM | 4.43 |
| CHEMBL8706 | CLORGILINE | IC50 | - | — | - |