Assay Detail
ADMET
CHEMBL2406718
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Cytotoxicity against HUVEC after 46 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structure-cytotoxic activity relationship of 3-arylideneflavanone and chromanone (E,Z isomers) and 3-arylflavones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.09 | 5.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL10072 | — | — | 1 | 5.27 |
| CHEMBL2402883 | — | — | 1 | 5.27 |
| CHEMBL10026 | — | — | 1 | 5.24 |
| CHEMBL2402880 | — | — | 1 | 5.14 |
| CHEMBL2402879 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL10072 | — | IC50 | = | 5410.0 | nM | 5.27 |
| CHEMBL2402883 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL10026 | — | IC50 | = | 5770.0 | nM | 5.24 |
| CHEMBL2402880 | — | IC50 | = | 7230.0 | nM | 5.14 |
| CHEMBL2402879 | — | IC50 | = | 29120.0 | nM | 4.54 |