Assay Detail
Binding
CHEMBL2410778
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse ERK2 pre-incubation for 15 mins before substrate addition measured after 60 mins by IMAP-FP assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
ERK2 Inhibitors May Provide Treatment for Cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 9.76 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2408789 | — | — | 1 | 9.82 |
| CHEMBL2408790 | — | — | 1 | 9.82 |
| CHEMBL2408788 | — | — | 1 | 9.65 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2408789 | — | IC50 | = | 0.1524 | nM | 9.82 |
| CHEMBL2408790 | — | IC50 | = | 0.1524 | nM | 9.82 |
| CHEMBL2408788 | — | IC50 | = | 0.2223 | nM | 9.65 |