Assay Detail
Binding
CHEMBL2411138
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human calmodulin expressed in Escherichia coli using M124C-mBBr fluorescent biosensor by spectrofluorometer analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Absolute configuration of acremoxanthone C, a potent calmodulin inhibitor from Purpureocillium lilacinum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.12 | 7.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2408940 | — | — | 1 | 7.74 |
| CHEMBL2408939 | — | — | 1 | 7.71 |
| CHEMBL71 | CHLORPROMAZINE | 4.0 | 1 | 5.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2408940 | — | Kd | = | 18.25 | nM | 7.74 |
| CHEMBL2408939 | — | Kd | = | 19.4 | nM | 7.71 |
| CHEMBL71 | CHLORPROMAZINE | Kd | = | 1240.0 | nM | 5.91 |