Assay Detail
Binding
CHEMBL2411426
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of myoglobin (unknown origin)-mediated arachidonic acid oxidation using [14C]AA as substrate after 3 hrs by GC/NICI/MS analysis
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.62 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2407813 | — | — | 1 | 5.92 |
| CHEMBL2407811 | — | — | 1 | 5.64 |
| CHEMBL112 | ACETAMINOPHEN | 4.0 | 1 | 5.64 |
| CHEMBL2407812 | — | — | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2407813 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL2407811 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL112 | ACETAMINOPHEN | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL2407812 | — | IC50 | = | 5300.0 | nM | 5.28 |