Assay Detail
Functional
CHEMBL2411608
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Antienteroviral activity against Human rhinovirus 2 infected in human HeLa Rh cells assessed as protection against virus-induced cytopathic effect after 2 to 3 days by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | rhinovirus A2 |
| Cell Type | HeLa Rh |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of a series of compounds with potent antiviral activity for the treatment of enterovirus infections.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.10 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29609 | PLECONARIL | 2.0 | 1 | 8.15 |
| CHEMBL2407818 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29609 | PLECONARIL | EC50 | = | 7.0 | nM | 8.15 |
| CHEMBL2407818 | — | EC50 | = | 9.0 | nM | 8.05 |