Assay Detail
Functional
CHEMBL2411684
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Cytotoxicity against human HT-29 cells after 72 hrs by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-29 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive constituents of Indigofera spicata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.58 | 9.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 9.22 |
| CHEMBL240545 | ROTENOLONE | — | 1 | 7.00 |
| CHEMBL429023 | ROTENONE | — | 1 | 6.52 |
| CHEMBL241806 | TEPHROSIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 0.6 | nM | 9.22 |
| CHEMBL240545 | ROTENOLONE | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL429023 | ROTENONE | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL241806 | TEPHROSIN | IC50 | > | 10000.0 | nM | - |