Assay Detail
Functional
CHEMBL2415668
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Metal chelating activity of the compound assessed as zinc affinity by UV spectroscopy
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and initial in vitro biological evaluation of two new zinc-chelating compounds: comparison with TPEN and PAC-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 8.19 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2414195 | — | — | 1 | 9.00 |
| CHEMBL591429 | PAC-1 | 1.0 | 1 | 7.38 |
| CHEMBL2414196 | — | — | 1 | - |
| CHEMBL1472575 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2414195 | — | Kd | = | 1.0 | nM | 9.00 |
| CHEMBL591429 | PAC-1 | Kd | = | 42.0 | nM | 7.38 |
| CHEMBL2414196 | — | Kd | = | 0.0002 | nM | - |
| CHEMBL1472575 | — | Kd | = | 2.6e-07 | nM | - |