Assay Detail
Functional
CHEMBL2421275
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Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | NCI-H460 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Apratoxin H and apratoxin A sulfoxide from the Red Sea cyanobacterium Moorea producens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.04 | 8.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501696 | APRATOXIN A | — | 1 | 8.60 |
| CHEMBL2419836 | — | — | 1 | 8.47 |
| CHEMBL2419835 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501696 | APRATOXIN A | IC50 | = | 2.5 | nM | 8.60 |
| CHEMBL2419836 | — | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL2419835 | — | IC50 | = | 89.9 | nM | 7.05 |