Assay Detail
Binding
CHEMBL2422044
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Inhibition of recombinant VIM-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using FC4 as substrate preincubated for 10 mins prior to substrate addition by fluorescence-based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Not specified |
| Cell Type | BL21-DE3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Assay platform for clinically relevant metallo-β-lactamases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.26 | 4.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2419267 | — | — | 1 | 4.26 |
| CHEMBL2419266 | — | — | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2419267 | — | IC50 | = | 55300.0 | nM | 4.26 |
| CHEMBL2419266 | — | IC50 | = | 54700.0 | nM | 4.26 |