Assay Detail
Functional
CHEMBL2422597
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Feline Herpes virus infected in cat CRFK cells assessed as inhibition of virus-induced cytopathic effect by MTS assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Felid alphaherpesvirus 1 |
| Cell Type | CRFK |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Regioselective synthesis of 6-substituted-2-amino-5-bromo-4(3H)-pyrimidinones and evaluation of their antiviral activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 10 | 5.94 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | 4.0 | 1 | 6.05 |
| CHEMBL2420195 | — | — | 1 | 5.82 |
| CHEMBL2420196 | — | — | 1 | - |
| CHEMBL2420194 | — | — | 1 | - |
| CHEMBL2420193 | — | — | 1 | - |
| CHEMBL2420192 | — | — | 1 | - |
| CHEMBL2420191 | — | — | 1 | - |
| CHEMBL2420190 | — | — | 1 | - |
| CHEMBL2420189 | — | — | 1 | - |
| CHEMBL2420188 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL182 | GANCICLOVIR | EC50 | = | 900.0 | nM | 6.05 |
| CHEMBL2420195 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL2420196 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420194 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420193 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420192 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420191 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420190 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420189 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL2420188 | — | EC50 | > | 100000.0 | nM | - |