Assay Detail
Binding
CHEMBL2424072
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Binding affinity to HSP90alpha (unknown origin) by fluorescence polarization assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Experimental and structural testing module to analyze paralogue-specificity and affinity in the Hsp90 inhibitors series.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 8.80 | 9.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2419341 | — | — | 1 | 9.15 |
| CHEMBL2419342 | — | — | 1 | 8.85 |
| CHEMBL1910764 | — | — | 1 | 8.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2419341 | — | Kd | = | 0.7 | nM | 9.15 |
| CHEMBL2419342 | — | Kd | = | 1.4 | nM | 8.85 |
| CHEMBL1910764 | — | Kd | = | 3.9 | nM | 8.41 |