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Assay Detail

CHEMBL2424289

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of HDAC11 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histone deacetylase 11 (CHEMBL3310)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Development and therapeutic implications of selective histone deacetylase 6 inhibitors.
Kalin JH, Bergman JA.
J Med Chem (2013) 56 : 6297 -6313
PubMed 23627282 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.47 6.72

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL227118 1 6.72
CHEMBL178456 1 6.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL227118 IC50 = 190.0 nM 6.72
CHEMBL178456 IC50 = 610.0 nM 6.21