Assay Detail
Binding
CHEMBL2426984
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine brain GSK-3alpha/beta using GS-1 peptide and [gamma-33P]ATP as substrate after 30 mins
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synthesis, resolution, and biological evaluation of atropisomeric (aR)- and (aS)-16-methyllamellarins N: unique effects of the axial chirality on the selectivity of protein kinases inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.14 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301226 | — | — | 1 | 8.30 |
| CHEMBL2425487 | — | — | 2 | 6.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301226 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL2425487 | — | IC50 | = | 210.0 | nM | 6.68 |
| CHEMBL2425487 | — | IC50 | = | 370.0 | nM | 6.43 |