Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2428072

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CypB PPIase activity (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Peptidyl-prolyl cis-trans isomerase B (CHEMBL2075)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Anti-inflammatory effects of extracellular cyclosporins are exclusively mediated by CD147.
Malesevic M, Gutknecht D, Prell E, Klein C, Schumann M, Nowak RA, Simon JC, Schiene-Fischer C, Saalbach A.
J Med Chem (2013) 56 : 7302 -7311
PubMed 23964991 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.45 7.45

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2424822 1 7.45

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2424822 Ki = 35.2 nM 7.45