Assay Detail
Binding
CHEMBL2428640
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of dCK (unknown origin) by steady-state kinetic assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.81 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2426574 | — | — | 1 | 9.30 |
| CHEMBL2426573 | — | — | 1 | 9.10 |
| CHEMBL2426558 | — | — | 1 | 8.82 |
| CHEMBL2426588 | — | — | 1 | 8.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2426574 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL2426573 | — | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL2426558 | — | Ki | = | 1.5 | nM | 8.82 |
| CHEMBL2426588 | — | Ki | = | 9.5 | nM | 8.02 |