Assay Detail
Functional
CHEMBL2428822
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Cytotoxicity against human IMR32 cells after 72 hrs by MTS assay
3
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | IMR-32 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, resolution, and biological evaluation of atropisomeric (aR)- and (aS)-16-methyllamellarins N: unique effects of the axial chirality on the selectivity of protein kinases inhibition.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.60 | 7.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301226 | — | — | 1 | 7.72 |
| CHEMBL2425487 | — | — | 2 | 6.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301226 | — | IC50 | = | 19.0 | nM | 7.72 |
| CHEMBL2425487 | — | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL2425487 | — | IC50 | = | 2000.0 | nM | 5.70 |