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Assay Detail

CHEMBL2429563

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human U2OS cells assessed as cell survival after 24 hrs by trypan blue exclusion assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type U2OS
Confidence 1 — Organism
Curated By Autocuration

Target

U2OS (CHEMBL615023)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthetic polyamines activating autophagy: effects on cancer cell death.
Minarini A, Zini M, Milelli A, Tumiatti V, Marchetti C, Nicolini B, Falconi M, Farruggia G, Cappadone C, Stefanelli C.
Eur J Med Chem (2013) 67 : 359 -366
PubMed 23887056 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.96 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2398522 1 5.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2398522 IC50 = 1100.0 nM 5.96