Assay Detail

CHEMBL2433137

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of Mycobacterium tuberculosis PtpB

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Mycobacterium tuberculosis
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Development of Mycobacterium tuberculosis whole cell screening hits as potential antituberculosis agents.

Cooper CB.
J Med Chem (2013) 56 : 7755 -7760
PubMed 23927683 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	2	6.41	6.66

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1765362	—	—	1	6.66
CHEMBL2431734	—	—	1	6.16

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1765362	—	Ki	=	220.0	nM	6.66
CHEMBL2431734	—	Ki	=	690.0	nM	6.16