Assay Detail
Binding
CHEMBL2434178
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of trypsin (unknown origin) using N-succinyl-phenylalanine-p-nitroanilide as substrate incubated for 20 mins prior to substrate addition by Dixon plot/ Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
A new trypsin inhibitory phthalic acid ester from Heliotropium strigosum
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 4.96 | 5.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL190503 | PHENYLMETHYLSULFONYLFLUORIDE | — | 1 | 5.00 |
| CHEMBL2430969 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL190503 | PHENYLMETHYLSULFONYLFLUORIDE | Ki | = | 10010.0 | nM | 5.00 |
| CHEMBL2430969 | — | Ki | = | 12100.0 | nM | 4.92 |