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Assay Detail

CHEMBL2434793

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Binding
Partial agonist activity at dopamine D3 receptor (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

D(3) dopamine receptor (CHEMBL234)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and binding affinity of new 1,4-disubstituted triazoles as potential dopamine D(3) receptor ligands.
Insua I, Alvarado M, Masaguer CF, Iglesias A, Brea J, Loza MI, Carro L.
Bioorg Med Chem Lett (2013) 23 : 5586 -5591
PubMed 24012118 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.70 9.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL484358 1 9.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL484358 Ki = 0.2 nM 9.70