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Assay Detail

CHEMBL2439306

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Non-competitive inhibition of mitochondrial Trypanosoma cruzi SQS
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma cruzi
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design, synthesis and biological evaluation of WC-9 analogs as antiparasitic agents.
Elicio PD, Chao MN, Galizzi M, Li C, Szajnman SH, Docampo R, Moreno SN, Rodriguez JB.
Eur J Med Chem (2013) 69 : 480 -489
PubMed 24090919 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.89 6.89
Ki 1 6.89 6.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL39581 2 6.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL39581 IC50 = 129.0 nM 6.89
CHEMBL39581 Ki = 129.0 nM 6.89