Assay Detail
Binding
CHEMBL2439828
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase assessed as L-DOPA conversion to melanin preincubated for 10 mins prior to substrate addition measured after 10 mins by spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Investigating the selectivity of metalloenzyme inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.40 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL121188 | TROPOLONE | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL121188 | TROPOLONE | IC50 | = | 400.0 | nM | 6.40 |