Assay Detail
Binding
CHEMBL2439895
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]Rauwolscine from human recombinant alpha2A-adrenoceptor expressed in MDCK cells after 90 mins by scintillation counting analysis
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | MDCK |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.53 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2436555 | — | — | 2 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2436555 | — | Ki | = | 283.0 | nM | 6.55 |
| CHEMBL2436555 | — | Ki | = | 316.23 | nM | 6.50 |