Assay Detail
Binding
CHEMBL2443398
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ketanserin from 5-HT2 in pig cerebral cortex
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Cerebral cortex |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Click chemistry based synthesis of dopamine D4 selective receptor ligands for the selection of potential PET tracers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 11 | 4.85 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2443009 | — | — | 1 | 5.19 |
| CHEMBL2443008 | — | — | 1 | 5.11 |
| CHEMBL2443006 | — | — | 1 | 5.09 |
| CHEMBL2443007 | — | — | 1 | 5.05 |
| CHEMBL2443004 | — | — | 1 | 5.00 |
| CHEMBL2443005 | — | — | 1 | 4.89 |
| CHEMBL2443001 | — | — | 1 | 4.75 |
| CHEMBL2443000 | — | — | 1 | 4.64 |
| CHEMBL2443003 | — | — | 1 | 4.60 |
| CHEMBL2443010 | — | — | 1 | 4.57 |
| CHEMBL2443002 | — | — | 1 | 4.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2443009 | — | Ki | = | 6400.0 | nM | 5.19 |
| CHEMBL2443008 | — | Ki | = | 7800.0 | nM | 5.11 |
| CHEMBL2443006 | — | Ki | = | 8200.0 | nM | 5.09 |
| CHEMBL2443007 | — | Ki | = | 9000.0 | nM | 5.05 |
| CHEMBL2443004 | — | Ki | = | 10000.0 | nM | 5.00 |
| CHEMBL2443005 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL2443001 | — | Ki | = | 18000.0 | nM | 4.75 |
| CHEMBL2443000 | — | Ki | = | 23000.0 | nM | 4.64 |
| CHEMBL2443003 | — | Ki | = | 25000.0 | nM | 4.60 |
| CHEMBL2443010 | — | Ki | = | 27000.0 | nM | 4.57 |
| CHEMBL2443002 | — | Ki | = | 38000.0 | nM | 4.42 |