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Assay Detail

CHEMBL2443610

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human CA2 by stopped-flow CO2 hydrase assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Carbonic anhydrase 2 (CHEMBL205)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structural study of the location of the phenyl tail of benzene sulfonamides and the effect on human carbonic anhydrase inhibition.
Güzel-Akdemir O, Biswas S, Lastra K, McKenna R, Supuran CT.
Bioorg Med Chem (2013) 21 : 6674 -6680
PubMed 24012377 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.82 7.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1614844 1 7.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1614844 Ki = 15.0 nM 7.82