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Assay Detail

CHEMBL2444663

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant Trypanosoma cruzi sterol 14-alpha-demethylase by spectrophotometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Trypanosoma cruzi
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agents.
Suryadevara PK, Racherla KK, Olepu S, Norcross NR, Tatipaka HB, Arif JA, Planer JD, Lepesheva GI, Verlinde CL, Buckner FS, Gelb MH.
Bioorg Med Chem Lett (2013) 23 : 6492 -6499
PubMed 24120539 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.31 6.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2440958 1 6.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2440958 Kd = 490.0 nM 6.31