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Assay Detail

CHEMBL2445273

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine liver beta-glucosidase assessed as inhibition of p-nitrophenol release by spectrophotometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Synthesis and biological evaluation of N-(2-fluorophenyl)-2β-deoxyfuconojirimycin acetamide as a potent inhibitor for α-l-fucosidases.
Kato A, Okaki T, Ifuku S, Sato K, Hirokami Y, Iwaki R, Kamori A, Nakagawa S, Adachi I, Kiria PG, Onomura O, Minato D, Sugimoto K, Matsuya Y, Toyooka N.
Bioorg Med Chem (2013) 21 : 6565 -6573
PubMed 24026016 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.15 5.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2442781 1 5.15
CHEMBL2442777 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2442781 IC50 = 7100.0 nM 5.15
CHEMBL2442777 IC50 = 754000.0 nM -