Assay Detail
Binding
CHEMBL2445937
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MAOB
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
In vitro structure-activity relationships of aplysinopsin analogs and their in vivo evaluation in the chick anxiety-depression model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.68 | 6.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463249 | — | — | 1 | 6.35 |
| CHEMBL404232 | APLYSINOPSIN | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463249 | — | IC50 | = | 447.0 | nM | 6.35 |
| CHEMBL404232 | APLYSINOPSIN | IC50 | = | 10017.0 | nM | 5.00 |