Assay Detail
Functional
CHEMBL2446443
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human PC3 cells assessed as growth inhibition after 3 days by WST-8 assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design and Synthesis of 4-(4-Benzoylaminophenoxy)phenol Derivatives As Androgen Receptor Antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.25 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2441107 | — | — | 1 | 5.25 |
| CHEMBL2441094 | — | — | 1 | 5.24 |
| CHEMBL409 | BICALUTAMIDE | 4.0 | 1 | - |
| CHEMBL2441092 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2441107 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL2441094 | — | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL409 | BICALUTAMIDE | IC50 | > | 10000.0 | nM | - |
| CHEMBL2441092 | — | IC50 | > | 10000.0 | nM | - |