Assay Detail
Binding
CHEMBL2446499
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Binding affinity to human recombinant carbonic anhydrase 2 by isothermal titration calorimetry
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.85 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2443190 | — | — | 1 | 8.00 |
| CHEMBL2443204 | — | — | 1 | 7.84 |
| CHEMBL2443194 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2443190 | — | Kd | = | 9.9 | nM | 8.00 |
| CHEMBL2443204 | — | Kd | = | 14.5 | nM | 7.84 |
| CHEMBL2443194 | — | Kd | = | 20.2 | nM | 7.70 |