Assay Detail
Functional
CHEMBL2447178
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MGC803 cells overexpressing LSD1 by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MGC-803 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Triazole-dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.98 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2334501 | — | — | 1 | 6.05 |
| CHEMBL2334497 | — | — | 1 | 5.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2334501 | — | IC50 | = | 890.0 | nM | 6.05 |
| CHEMBL2334497 | — | IC50 | = | 1260.0 | nM | 5.90 |