Assay Detail
Binding
CHEMBL2447762
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Inhibition of CK2 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Discovery and characterization of synthetic 4'-hydroxyflavones-New CK2 inhibitors from flavone family.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.22 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31574 | FISETIN | 2.0 | 1 | 6.46 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 6.26 |
| CHEMBL28 | APIGENIN | — | 1 | 6.10 |
| CHEMBL164 | MYRICETIN | — | 1 | 6.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31574 | FISETIN | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL50 | QUERCETIN | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL28 | APIGENIN | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL164 | MYRICETIN | IC50 | = | 920.0 | nM | 6.04 |