Assay Detail
Functional
CHEMBL3049976
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Herbicidal activity against Cucumis sativus Jin 4 (cucumber) assessed as inhibition of stem growth after 3 days
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cucumis sativus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Studies of O,O-dimethyl α-(2,4-dichlorophenoxyacetoxy)ethylphosphonate (HW02) as a new herbicide. 1. Synthesis and herbicidal activity of HW02 and analogues as novel inhibitors of pyruvate dehydrogenase complex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 16 | 4.90 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2227962 | — | — | 1 | 5.30 |
| CHEMBL2227963 | — | — | 1 | 5.17 |
| CHEMBL2227911 | CLACYFOS | — | 1 | 5.12 |
| CHEMBL2227928 | — | — | 1 | 5.11 |
| CHEMBL2227682 | — | — | 1 | 5.05 |
| CHEMBL2227964 | — | — | 1 | 5.03 |
| CHEMBL367623 | 2,4-DICHLOROPHENOXYACETIC ACID | — | 1 | 4.99 |
| CHEMBL2227965 | — | — | 1 | 4.87 |
| CHEMBL2227966 | — | — | 1 | 4.86 |
| CHEMBL2227916 | — | — | 1 | 4.85 |
| CHEMBL2227967 | — | — | 1 | 4.75 |
| CHEMBL2227968 | — | — | 1 | 4.59 |
| CHEMBL2227969 | — | — | 1 | 4.52 |
| CHEMBL2227970 | — | — | 1 | 4.35 |
| CHEMBL2227972 | — | — | 1 | - |
| CHEMBL2227971 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2227962 | — | IC50 | = | 5020.0 | nM | 5.30 |
| CHEMBL2227963 | — | IC50 | = | 6740.0 | nM | 5.17 |
| CHEMBL2227911 | CLACYFOS | IC50 | = | 7560.0 | nM | 5.12 |
| CHEMBL2227928 | — | IC50 | = | 7790.0 | nM | 5.11 |
| CHEMBL2227682 | — | IC50 | = | 8950.0 | nM | 5.05 |
| CHEMBL2227964 | — | IC50 | = | 9340.0 | nM | 5.03 |
| CHEMBL367623 | 2,4-DICHLOROPHENOXYACETIC ACID | IC50 | = | 10140.0 | nM | 4.99 |
| CHEMBL2227965 | — | IC50 | = | 13400.0 | nM | 4.87 |
| CHEMBL2227966 | — | IC50 | = | 13700.0 | nM | 4.86 |
| CHEMBL2227916 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL2227967 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL2227968 | — | IC50 | = | 25700.0 | nM | 4.59 |
| CHEMBL2227969 | — | IC50 | = | 30100.0 | nM | 4.52 |
| CHEMBL2227970 | — | IC50 | = | 44300.0 | nM | 4.35 |
| CHEMBL2227972 | — | IC50 | = | 164000.0 | nM | - |
| CHEMBL2227971 | — | IC50 | = | 109000.0 | nM | - |