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Assay Detail

CHEMBL3052380

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]alpha-bungarotoxin from nicotinic acetylcholine receptor in Apis mellifera (honey bee) head membrane
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Apis mellifera
Tissue Head
Subcellular Membrane
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Insecticidal Activity and Selective Toxicity of Chloronicotinyl Compounds Having Thiomethyl Groups
KOYANAGI T, MORITA M, OKADA H
J Pestic Sci (2000) 25 : 37 -39
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.83 6.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1391421 1 6.96
CHEMBL2270480 1 4.69

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1391421 IC50 = 110.0 nM 6.96
CHEMBL2270480 IC50 = 20380.0 nM 4.69