Assay Detail
Functional
CHEMBL3053146
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Vesicular stomatitis virus infected Hela cells assessed as inhibition of virus-induced cytopathicity
15
Total Activities
15
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Vesicular stomatitis virus |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Vesicular stomatitis virus (CHEMBL613739) ↗| Type | ORGANISM |
| Organism | Vesicular stomatitis virus |
Publication
The novel amidocarbamate derivatives of ketoprofen: synthesis and biological activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 14 | - | - |
| EC50 | 1 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1170394 | — | — | 1 | 5.52 |
| CHEMBL153 | TROLOX | — | 1 | - |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | — | 1 | - |
| CHEMBL145 | CAFFEIC ACID | 3.0 | 1 | - |
| CHEMBL571 | KETOPROFEN | 4.0 | 1 | - |
| CHEMBL1172546 | — | — | 1 | - |
| CHEMBL1171686 | — | — | 1 | - |
| CHEMBL1170395 | — | — | 1 | - |
| CHEMBL1170146 | — | — | 1 | - |
| CHEMBL1172093 | — | — | 1 | - |
| CHEMBL1172092 | — | — | 1 | - |
| CHEMBL1172091 | — | — | 1 | - |
| CHEMBL1170348 | — | — | 1 | - |
| CHEMBL1170347 | — | — | 1 | - |
| CHEMBL1172493 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1170394 | — | EC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL153 | TROLOX | Activity | - | — | - | |
| CHEMBL52 | NORDIHYDROGUAIARETIC ACID | Activity | - | — | - | |
| CHEMBL145 | CAFFEIC ACID | Activity | - | — | - | |
| CHEMBL571 | KETOPROFEN | Activity | - | — | - | |
| CHEMBL1172546 | — | Activity | - | — | - | |
| CHEMBL1171686 | — | Activity | - | — | - | |
| CHEMBL1170395 | — | Activity | - | — | - | |
| CHEMBL1170146 | — | Activity | - | — | - | |
| CHEMBL1172093 | — | Activity | - | — | - | |
| CHEMBL1172092 | — | Activity | - | — | - | |
| CHEMBL1172091 | — | Activity | - | — | - | |
| CHEMBL1170348 | — | Activity | - | — | - | |
| CHEMBL1170347 | — | Activity | - | — | - | |
| CHEMBL1172493 | — | Activity | - | — | - |