Assay Detail
Binding
CHEMBL3053589
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of DPP-4 (unknown origin) assessed as inhibition of endomorphin-1 degradation after 30 min
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Kinetic studies of novel inhibitors of endomorphin degrading enzymes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.66 | 5.66 |
| Inhibition | 3 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL214381 | DIPROTIN A | — | 2 | 5.66 |
| CHEMBL2261077 | — | — | 2 | - |
| CHEMBL2261078 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL214381 | DIPROTIN A | Ki | = | 2200.0 | nM | 5.66 |
| CHEMBL2261077 | — | Ki | = | 270000.0 | nM | - |
| CHEMBL2261078 | — | Ki | = | 420000.0 | nM | - |
| CHEMBL2261077 | — | Inhibition | = | 39.1 | % | - |
| CHEMBL2261078 | — | Inhibition | = | 26.7 | % | - |
| CHEMBL214381 | DIPROTIN A | Inhibition | = | 96.8 | % | - |