Assay Detail
Binding
CHEMBL3056015
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of NLWAAQRYGRELRRMSD-K(FITC)-FVD from Bcl-2 (unknown origin) by fluorescence polarization assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Molecular docking study on anticancer activity of plant-derived natural products
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 6.47 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL483083 | CATECHIN GALLATE | — | 1 | 6.64 |
| CHEMBL264938 | GALLOCATECHIN GALLATE | — | 1 | 6.63 |
| CHEMBL2260476 | THEAFLAVANIN | — | 1 | 6.54 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | 3.0 | 1 | 6.47 |
| CHEMBL36327 | EPICATECHIN GALLATE | — | 1 | 6.40 |
| CHEMBL346119 | THEAFLAVIN | — | 1 | 6.16 |
| CHEMBL125743 | GALLOCATECHIN | — | 1 | - |
| CHEMBL47386 | EPIGALLOCATECHIN | — | 1 | - |
| CHEMBL583912 | (-)-EPICATECHIN | 2.0 | 1 | - |
| CHEMBL206452 | CATECHIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL483083 | CATECHIN GALLATE | Ki | = | 230.0 | nM | 6.64 |
| CHEMBL264938 | GALLOCATECHIN GALLATE | Ki | = | 235.0 | nM | 6.63 |
| CHEMBL2260476 | THEAFLAVANIN | Ki | = | 286.0 | nM | 6.54 |
| CHEMBL297453 | EPIGALOCATECHIN GALLATE | Ki | = | 335.0 | nM | 6.47 |
| CHEMBL36327 | EPICATECHIN GALLATE | Ki | = | 400.0 | nM | 6.40 |
| CHEMBL346119 | THEAFLAVIN | Ki | = | 690.0 | nM | 6.16 |
| CHEMBL125743 | GALLOCATECHIN | Ki | > | 100000.0 | nM | - |
| CHEMBL47386 | EPIGALLOCATECHIN | Ki | > | 100000.0 | nM | - |
| CHEMBL583912 | (-)-EPICATECHIN | Ki | > | 100000.0 | nM | - |
| CHEMBL206452 | CATECHIN | Ki | > | 100000.0 | nM | - |