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Assay Detail

CHEMBL3056573

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of CDK2 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 2 (CHEMBL301)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Molecular docking study on anticancer activity of plant-derived natural products
Phosrithong N, Ungwitayatorn J
Med Chem Res (2010) 19 : 817 -835
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 8.76 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL388978 STAUROSPORINE 1 10.00
CHEMBL574737 UCN-01 2.0 1 7.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL388978 STAUROSPORINE IC50 = 0.1 nM 10.00
CHEMBL574737 UCN-01 IC50 = 30.0 nM 7.52