Assay Detail
ADMET
CHEMBL3057005
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Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells by neutral red staining
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis of curcumin and ethylcurcumin bioconjugates as potential antitumor agents
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.89 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2259872 | — | — | 1 | 5.30 |
| CHEMBL2259876 | — | — | 1 | 4.96 |
| CHEMBL2260081 | — | — | 1 | 4.96 |
| CHEMBL2260080 | — | — | 1 | 4.94 |
| CHEMBL2260077 | — | — | 1 | 4.90 |
| CHEMBL2260082 | — | — | 1 | 4.82 |
| CHEMBL2260076 | — | — | 1 | 4.82 |
| CHEMBL2260073 | — | — | 1 | 4.71 |
| CHEMBL2260089 | — | — | 1 | 4.64 |
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | - |
| CHEMBL2260091 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2259872 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL2259876 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL2260081 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL2260080 | — | IC50 | = | 11500.0 | nM | 4.94 |
| CHEMBL2260077 | — | IC50 | = | 12500.0 | nM | 4.90 |
| CHEMBL2260082 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL2260076 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL2260073 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL2260089 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL53463 | DOXORUBICIN | IC50 | > | 5000.0 | nM | - |
| CHEMBL2260091 | — | IC50 | > | 25000.0 | nM | - |