Assay Detail
Binding
CHEMBL3061794
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Inhibition of beta-lactamase SHV-61
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Homology modeling and docking study of recent SHV type -lactamses with traditional and novel inhibitors: an in silico approach to combat problem of multiple drug resistance in various infections
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 4.77 | 4.83 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1673092 | PENEM-2 | — | 1 | 4.83 |
| CHEMBL2236666 | — | — | 1 | 4.81 |
| CHEMBL1673091 | PENEM-1 | — | 1 | 4.67 |
| CHEMBL777 | CLAVULANIC ACID | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1673092 | PENEM-2 | Ki | = | 14690.0 | nM | 4.83 |
| CHEMBL2236666 | — | Ki | = | 15570.0 | nM | 4.81 |
| CHEMBL1673091 | PENEM-1 | Ki | = | 21430.0 | nM | 4.67 |
| CHEMBL777 | CLAVULANIC ACID | Ki | = | 337130.0 | nM | - |