Assay Detail
Binding
CHEMBL3062225
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Binding affinity to 5-HT6 receptor (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
5-ZATRYPTAMINE ANALOGS AS h5-HT6 SEROTONIN RECEPTOR LIGANDS
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.07 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL94093 | — | — | 1 | 9.10 |
| CHEMBL76237 | — | — | 1 | 8.68 |
| CHEMBL328816 | — | — | 1 | 7.92 |
| CHEMBL267615 | — | — | 1 | 7.80 |
| CHEMBL7318 | — | — | 1 | 7.70 |
| CHEMBL433461 | — | — | 1 | 7.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL94093 | — | Ki | = | 0.8 | nM | 9.10 |
| CHEMBL76237 | — | Ki | = | 2.1 | nM | 8.68 |
| CHEMBL328816 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL267615 | — | Ki | = | 16.0 | nM | 7.80 |
| CHEMBL7318 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL433461 | — | Ki | = | 58.0 | nM | 7.24 |