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Assay Detail

CHEMBL3067620

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antifungal activity against Phomopsis obscurans assessed as inhibition of fungal growth measured after 120 hr by 96-well microdilution assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Phomopsis obscurans
Confidence 1 — Organism
Curated By Autocuration

Target

Phomopsis obscurans (CHEMBL2367277)
Type ORGANISM
Organism Phomopsis obscurans

Publication

Isolation and identification of antifungal fatty acids from the basidiomycete Gomphus floccosus.
Cantrell CL, Case BP, Mena EE, Kniffin TM, Duke SO, Wedge DE.
J Agric Food Chem (2008) 56 : 5062 -5068
PubMed 18557621 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.24 5.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL388676 CAPTAN 1 5.96
CHEMBL2253146 1 5.35
CHEMBL1230670 1 5.00
CHEMBL465240 1 4.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL388676 CAPTAN IC50 = 1100.0 nM 5.96
CHEMBL2253146 IC50 = 4500.0 nM 5.35
CHEMBL1230670 IC50 = 10000.0 nM 5.00
CHEMBL465240 IC50 = 23000.0 nM 4.64